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Cytidine monophosphate kinase in complex with cytosine diphosphate
Overall structure of the cytidine monophosphate kinase in complex with cytosine diphosphate determined by X-ray crystallography [1]. The fragment including an antiparallel b-sheet and two a-helices (in blue) was not observed in the electron density map but could be characterized by NMR spectroscopy.
[1] Briozzo, P., et al., Structures of Escherichia coli CMP kinase alone and in complex with CDP: a new fold of the nucleoside monophosphate binding domain and insights into cytosine nucleotide specificity. Structure, 1998, 6: p. 1517-1527.