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Model of human procentriole assembly

Model of human procentriole assembly

a, The first step of procentriole assembly involves the formation of a stalk at the proximal end of the mature centriole (b). c, The cartwheel assembles from this stalk and organises the procentriolar wall, where some A-microtubules start growing from the γ-TuRCs. d, Enlargment of the procentriole shown in (c). e, Before completion of the nine A-microtubule round, some B-microtubules start growing from the wall of A microtubules. f, B-microtubules grow bidirectionally, and C-microtubules start growing from the wall of the B-microtubules. g, C-microtubules grow bidirectionally until the B- and C-microtubules reach the proximal end of the A-microtubule. h, Growth continues at the distal end until completion of the microtubule triplet blades.