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Structure of Lqh-8/6 toxin

Structure of Lqh-8/6 toxin

Simplified three-dimensional structure, determined by NMR, of the major conformer of Lqh-8/6 toxin from a scorpion venom [1]. A second conformer, in almost the same proportion is characterized by a cis isomer of a peptidyl-prolyl peptide bond.

[1] Adjadj, E., et al., Solution structure of Lqh-8/6, a toxin-like peptide from a scorpion venom. Structural heterogeneity induced by proline cis/trans isomerization. European Journal of Biochemistry (1997), 246, 218-227.